The presence of immunoglobulin G (IgG) antibodies particular to varicella-zoster virus (VZV) in serum signifies prior publicity to the virus, both by way of pure an infection (chickenpox or shingles) or vaccination. These antibodies are produced by the physique’s immune system as a protection towards VZV. A detectable degree sometimes signifies immunity. For instance, a optimistic laboratory take a look at outcome for this kind of antibody confirms that a person has been beforehand contaminated or immunized towards the virus.
The detection of those antibodies is essential for assessing a person’s immunity standing, guiding vaccination selections, and understanding the epidemiology of varicella-zoster virus infections. Traditionally, assessing immunity relied on self-reported historical past of chickenpox, which could be unreliable. This laboratory take a look at gives a extra goal and correct measure. Moreover, data of an people immune standing is especially necessary for people who’re immunocompromised or pregnant, as VZV an infection can pose important dangers to those populations.
