Fetal fraction represents the proportion of cell-free fetal DNA circulating in a pregnant individual’s blood. Non-Invasive Prenatal Testing (NIPT) analyzes this DNA to display screen for sure chromosomal abnormalities within the creating fetus. For instance, if a pattern has a fetal fraction of 10%, it signifies that 10% of the cell-free DNA within the maternal blood pattern originates from the placenta, which is mostly consultant of the fetal genome.
The amount of fetal DNA current is vital for the accuracy and reliability of NIPT outcomes. A enough quantity ensures that the check has sufficient genetic materials to research and minimizes the danger of false unfavourable outcomes. Traditionally, low quantities may result in check failure, requiring a redraw and doubtlessly delaying outcomes. Understanding the proportion of this DNA helps clinicians assess the check’s validity and make knowledgeable selections relating to affected person care.
